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Product Categories
Pathological antibody
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Product Name
BAP1 Rabbit mAb
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Background
This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]
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Alternative Names
BAP-1;UCHL2; hucep-6; HUCEP-13;BRCA1-associated protein 1;Cerebral protein 6
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Immunogen
A synthesized peptide derived from human BAP1.
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Dilution Ratio
IHC: 1/100-1/200
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Molecular Weight
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Gene Name
BAP-1
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Host
Rabbit
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Reactivity
Human
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Conjugation
Unconjugated
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Application
IHC-P
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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SwissProt ID
Q92560
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Purification
Affinity Purified
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Clonality No.
R08-5M1
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Clonality
Monoclonal Antibody
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Isotype
IgG
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Form
Liquid
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Research Field
Cell Biology
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Gene ID
8314
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Modification
Unmodified